|
Symbol Name ID |
Cyp19a1
cytochrome P450, family 19, subfamily a, polypeptide 1 MGI:88587 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Enlarged polycystic ovaries |
Dysgerminoma |
Ovarian papillary adenocarcinoma |
Endometrial carcinoma |
Amenorrhea |
Oligomenorrhea |
| Disease(s) Associated with CYP19A1 | ||||||
| endometrial cancer | ||||||
| ovarian cancer | ||||||
| polycystic ovary syndrome |
| Mouse Phenotypes | reproductive system phenotype |
ovary hemorrhage |
oligozoospermia |
abnormal acrosome assembly |
abnormal male germ cell morphology |
abnormal spermatid morphology |
decreased male germ cell number |
multinucleated giant male germ cells |
increased male germ cell apoptosis |
increased granulosa cell apoptosis |
increased ovary apoptosis |
asthenozoospermia |
increased prostate gland anterior lobe weight |
prostate gland anterior lobe hyperplasia |
increased prostate gland dorsolateral lobe weight |
prostate gland dorsolateral lobe hyperplasia |
increased prostate gland ventral lobe weight |
increased prostate gland weight |
enlarged prostate gland |
prostate gland hyperplasia |
prostate gland ventral lobe hyperplasia |
increased seminal vesicle weight |
abnormal ovary morphology |
absent corpus luteum |
abnormal mature ovarian follicle morphology |
absent ovarian follicles |
impaired ovarian folliculogenesis |
abnormal tertiary ovarian follicle morphology |
ovarian follicular cyst |
ovary cyst |
abnormal seminiferous tubule morphology |
abnormal seminiferous tubule epithelium morphology |
increased Leydig cell number |
decreased testis weight |
enlarged testis |
abnormal prostate gland physiology |
enlarged clitoris |
abnormal labium morphology |
thin endometrium |
thin myometrium |
abnormal uterus development |
decreased uterus weight |
small uterus |
uterus hypoplasia |
abnormal spermatogenesis |
abnormal spermiogenesis |
arrest of spermiogenesis |
abnormal male reproductive system morphology |
abnormal epididymis morphology |
abnormal primary sex determination |
abnormal reproductive system physiology |
abnormal copulation |
failure of superovulation |
anovulation |
impaired luteinization |
female infertility |
male infertility |
reduced male fertility |
failure of ejaculation |
|
| Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cyp19a1tm1Esi/Cyp19a1tm1Esi | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cyp19a1tm1Sih/Cyp19a1tm1Sih | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cyp19a1tm1Toda/Cyp19a1tm1Toda | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cyp19a1tm2.1(cre)Shah/Cyp19a1tm2.1(cre)Shah | * | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Tg(Cyp19)C2-3Rrte/0 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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